产品货号：
Z28123
中文名称：
Thrombospondin 1/THBS1抗体
英文名称：
Anti-Thrombospondin 1/THBS1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Thrombospondin 1/THBS1 Antibody |
| 指标别名 | THBS;THBS 1;THBS1;thrombospondin 1;Thrombospondin-1;TSP;TSP 1;TSP1;TSP-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | THBS1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Thrombospondin recombinant protein (Position:D27-H112).Human Thrombospondin shares 81.4% amino acid (aa) sequence identity with mouse Thrombospondin. |
| 实际分子量 | 129KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | THBS1 is also known as Thrombospondin 1,TSP1.The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein.It is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.This protein can bind to fibrinogen,fibronectin,laminin,type V collagen and integrins alpha-V/beta-1.It has been shown to play roles in platelet aggregation,angiogenesis,and tumorigenesis.In addition,the thrombospondin-1 protein is a member of the thrombospondinfamily.It is a multi-domain matrix glycoprotein that has been shown to be a natural inhibitor of neovascularization and tumorigenesis in healthy tissue.Both positive and negative modulation of endothelial cell adhesion,motility,and growth have been attributed to TSP1.This should not be surprising considering that TSP1 interacts with at least 12 cell adhesion receptors,including CD36,αv integrins,β1 integrins,syndecan,and integrin-associated protein (IAP or CD47).It also interacts with numerous proteases involved in angiogenesis,including plasminogen,urokinase,matrix metalloproteinase,thrombin,cathepsin,and elastase. |
| Uniprot ID | P07996 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 ELISA 1:100～1000 |
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